Pradaxa is a drug that is being prescribed as an alternative for Warfarin, another blood thinner. The first choice of blood thinner would be Warfarin, but Pradaxa has begun to take its place because the necessity of performing frequent blood tests does not exist with Pradaxa as it does with Warfarin. Both drugs work equally as well with the difference being that Pradaxa’s effects are irreversible. Before they decide on either one, physicians must carefully consider the advantages and disadvantages of both. As a result of numerous reports of internal bleeding side effects caused by Pradaxa, several Pradaxa Lawsuits have been filed in order to get victims compensation for their injuries.
Pradaxa can safely be taken in doses of 12.5 milligrams up to 300 milligrams two times per day as was discovered in a study done in 2004. If Pradaxa is being prescribed to prevent thrombosis, doses between 150 and 220 milligrams are considered to have a safety profile equivalent to the drug, Enoxaparin.
When taken with fatty foods, Pradaxa has a longer trajectory into the bloodstream. After the medication has been fully absorbed, blood concentrations remain as expected. If patients are using proton pump inhibitors for the treatment of acid reflux, they will experience a delay in absorption to some degree. These inhibitors also have the effect of delaying the medication’s release from the body, causing patients to have an increased amount of the anticoagulant in their bloodstreams.
Studies Done on Pradaxa
Two studies done on Pradaxa are worthy of mention. The RE-LY study was performed on patients with atrial fibrillation. The researchers sought to determine if Pradaxa was as effective and safe as Warfarin for these patients. With 110 milligrams of Pradaxa, the effectiveness and safety was equal to Warfarin. When the dose was increased to 150 milligrams two times a day, Pradaxa outperformed Warfarin. Undesired bleeding began at the same rate for Pradaxa as for Warfarin when given at the higher dose.
RE-COVER, the second study, used patients with acute venous thromboembolism to compare the two drugs. Those with the aforementioned condition suffer from blood clots, but while taking Pradaxa, less minor bleeding occurred. A number of patients had to stop taking Pradaxa because they experienced an increase in dyspepsia.
The Expiration Date
To help keep Pradaxa from expiring, the pills are placed in a bottle with a special cap because they are highly susceptible to humidity. Even so, the medication only lasts for 30 days after patients open their bottles. It’s possible that the drug could last as long as 60 days after the bottle has been opened, and the Food and Drug Administration (FDA) is currently reviewing this possibility.
TOOK PRADAXA AND SUFFERED FROM INTERNAL BLEEDING?
If you have taken Pradaxa and suffered from internal bleeding, you may be entitled to collect significant financial compensation by participating in the Pradaxa lawsuits. To find out if you have a case, contact our expert Pradaxia side effect lawyers for a free no obligation consultation by completing the form on this page or calling 1-800-905-2751.